Cavendish Hall was constructed on a tiny island in the center of Lake Talutah, in upstate New York, in 1841. Unknown to its founder, Elihu Cavendish, beneath Lake Talutah lay a massive underground temple where the Ogdru Jahad had been worshiped centuries before.
In 1992, the last of the Cavendish line, the three sons of the widow Emma Cavendish, were transformed into frog monsters due to their encounter with Grigori Rasputin and one of the 369 Ogdru Hem, called Sadu-Hem. The brothers and arctic explorer Sven Olafson were all transformed and enslaved to Rasputin and he brought them back to Cavendish Hall. B.P.R.D. agents Hellboy, Abe Sapien, and Liz Sherman investigated Cavendish Hall and circumstances led to the destruction of the manor.